Abstract No. 567 Safety and Efficacy of Percutaneous Management of Acute Cholangitis

Acute cholangitis can lead to severe complications if poorly managed. Peroral endoscopic biliary drainage is not feasible in some patients, such as those with altered anatomy. Interventional radiology (IR) play a significant role by performing transhepatic/transjejunal these patients. This study aims describe interventions performed patients acute and the impact of interventions. Percutaneous were 449 consecutive between 2009-2021. Of these, 69 (15%) (73 cases) had before intervention. The mean age was 61.8 (range, 18-94), 36 males, 31 benign etiologies (38 malignant), 30 prior hepatobiliary surgeries, 35 ERCPs, 27 stents. Tokyo guidelines used grade cholangitis. Paired samples Wilcoxon test utilized compare pre- 1-2 months post-white blood cell (WBC) count, total bilirubin, alkaline phosphatase (ALP). Twenty-four (33%) cases 1 cholangitis, 18 (25%) 2 (42%) 3 according guidelines. average time from presentation first IR intervention 3.96 days (range 0-13 days). Biliary drains placed 70 (96%) cases, cholangioplasty 14 (19%), stents 4 (5%) session. median decrease post-intervention WBC ALP 2.9 × 109/L, 1.7 mg/dL 155 IU/L, respectively (P = 0.14, 0.006 0.001, respectively). duration hospital stay after 9.13 0-69 days), 21 (29%) admitted ICU. In progressed sepsis 23/31 (74%) resolved within week intervention, whereas 8/31 (26%) two weeks Major complication seen one (1%) case (bleeding, managed embolization) minor (e.g., pericatheter leak/occlusion, malpositioned drain) 22 (30%) cases. plays an essential managing which needs urgent diagnosis treatment. safe effective management